Small-Molecule Novel Drug Ingredients Lab

The “Small-Molecule Novel Drug Ingredients Lab” project aims to establish a state-of-the-art facility for developing and pilot-scale manufacturing of active pharmaceutical ingredients (APIs) for early-stage (Phase I) clinical trials. This new lab will include four units: a cGMP suite for handling APIs at pilot scale, synthetic chemistry areas for 100 g to kilogram-scale work, and an analytical chemistry unit.

Project supported equipment list

EquipmentPurposeServices
5 kg flashRapid purification of target compound mixtures in R&D or pilot processes
150L jacketed reactorTemperature-controlled reactions at scale for small-molecule synthesis
Preparative Flash Chromatography with an ELSD marksPurification of non-UV-active compounds with evaporative light-scattering detection